Selected publications

• Sedlak D, Tuma R, Kolla JN, Mokhamatam RB, Bahrova L, Lisova M, Bittova L, Jindra M (2024) Unique and common agonists activate the insect juvenile hormone receptor and the human AHR. J Mol Biol 437, 168883. https://doi.org/10.1016/j.jmb.2024.168883

• Jindra M, Tumova S, Bittova L, Tuma R, Sedlak D (2024) Agonist-dependent action of the juvenile hormone receptor. Curr. Opin. Insect Sci. 65, 101234. https://doi.org/10.1016/j.cois.2024.101234

• Tumova S, Dolezel D, Jindra M (2024) Conserved and unique roles of bHLH-PAS transcription factors in insects - From clock to hormone reception. J Mol Biol 436, 168332. https://doi.org/10.1016/j.jmb.2023.168332

• Tumova S, Jindra M (2023) Ligand-dependent protein interactions of the juvenile hormone receptor captured in real time. FEBS J 290, 2881-2894. https://doi.org/10.1111/febs.16719
  

• Tumova S, Milacek M, Snajdr I, Muthu M, Tuma R, Reha D, Jedlicka P, Bittova L, Novotna A, Majer P, Sedlak D, Jindra M (2022) Unique peptidic agonists of a juvenile hormone receptor with species-specific effects on insect development and reproduction. Proc Natl Acad Sci USA 119, e2215541119. https://doi.org/10.1073/pnas.2215541119
  

• Jindra M, McKinstry WJ, Nebl T, Bittova L, Ren B, Shaw J, Phan T, Lu L, Low JKK, Mackay JP, Sparrow LG, Lovrecz GO, Hill RJ (2021) Purification of an insect juvenile hormone receptor complex enables insights into its post-translational phosphorylation. J Biol Chem 297, 101387.  https://doi.org/10.1016/j.jbc.2021.101387

• Nouzova M, Edwards MJ, Michalkova V, Ramirez CE, Ruiz M, Areiza M, DeGennaro M, Fernandez-Lima F, Feyereisen R, Jindra M, Noriega FG (2021) Epoxidation of juvenile hormone was a key innovation improving insect reproductive fitness. Proc Natl Acad Sci USA 118, e2109381118. https://doi.org/10.1073/pnas.2109381118
  

• Milacek M, Bittova L, Tumova S, Luksan O, Hanus R, Kyjakova P, Machara A, Marek A, Jindra M (2021) Binding of de novo synthesized radiolabeled juvenile hormone (JH III) by JH receptors from the Cuban subterranean termite Prorhinotermes simplex and the German cockroach Blattella germanica. Insect Biochem Mol Biol 139, 103671. https://doi.org/10.1016/j.ibmb.2021.103671

• Jindra M, Tumova S, Milacek M, Bittova L (2021) A decade with the juvenile hormone receptor. Adv Insect Physiol 60, 37-85. https://doi.org/10.1016/bs.aiip.2021.03.001
  

• Jindra M, Bittova L (2020) The juvenile hormone receptor as a target of juvenoid "insect growth regulators". Arch Insect Biochem Physiol 103, e21615 https://doi.org/10.1002/arch.21615

• Jindra M (2019) Where did the pupa come from? The timing of juvenile hormone signalling supports homology between stages of hemimetabolous and holometabolous insects. Phil Trans R Soc B 374, 20190064. https://doi.org/10.1098/rstb.2019.0064

• Bittova L, Jedlicka P, Dracinsky M, Kirubakaran P, Vondrasek J, Hanus R, Jindra M (2019) Exquisite ligand stereoselectivity of a Drosophila juvenile hormone receptor contrasts with its broad agonist repertoire. J Biol Chem 294, 410-423.

• Donohoe CD, Csordas G, Correia A, Jindra M, Klein C, Habermann B, Uhlirova M (2018) Atf3 links loss of epithelial polarity to defects in cell differentiation and cytoarchitecture. PLoS Genet 14, e1007241.

• Jindra M (2016) Something "hairy" in juvenile hormone signaling for mosquito reproduction. Proc Natl Acad Sci USA 113, 1474-1476. (Commentary)

• Jindra M, Belles X, Shinoda T (2015) Molecular basis of juvenile hormone signaling. Curr Opin Insect Sci 11, 39-46.

• Jindra M, Uhlirova M, Charles JP, Smykal V, Hill RJ (2015) Genetic evidence for function of the bHLH-PAS protein Gce/Met as a juvenile hormone receptor. PLoS Genet 11, e1005394.

• Smykal V, Daimon T, Kayukawa T, Takaki K, Shinoda T, Jindra M (2014) Importance of juvenile hormone signaling arises with competence of insect larvae to metamorphose. Dev Biol 390, 221-230.

• Smykal V, Bajgar A, Provaznik J, Fexova S, Buricova M, Takaki K, Hodkova M, Jindra M, Dolezel D (2014) Juvenile hormone signaling during reproduction and development of the linden bug, Pyrrhocoris apterus. Insect Biochem Mol Biol 45, 69-76.

• Claudius AK, Romani P, Lamkemeyer T, Jindra M, Uhlirova M (2014) Unexpected role of the steroid-deficiency protein Ecdysoneless in pre-mRNA splicing. PLoS Genet 10, e1004287.

• Bajgar A, Jindra M, Dolezel D (2013) Autonomous regulation of the insect gut by circadian genes acting downstream of juvenile hormone signaling. Proc Natl Acad Sci USA 110, 4416-4421.

• Jindra M, Palli SR, Riddiford LM (2013) The juvenile hormone signaling pathway in insect development. Annu Rev Entomol 58, 181-204.

• Rynes J, Donohoe CD, Frommolt P, Brodesser S, Jindra M, Uhlirova M (2012) Activating transcription factor 3 regulates immune and metabolic homeostasis. Mol Cell Biol 32, 3949-3962.

• Feyereisen R, Jindra M (2012) The silkworm coming of age - early. PLoS Genet 8, e1002591. (Commentary)

• Charles JP, Iwema T, Epa VC, Takaki K, Rynes J, Jindra M (2011) Ligand-binding properties of a juvenile hormone receptor, Methoprene-tolerant. Proc Natl Acad Sci USA 108, 21128-21133.

• Konopova B, Smykal V, Jindra M (2011) Common and distinct roles of juvenile hormone signaling genes in metamorphosis of holometabolous and hemimetabolous insects. PLoS One 6, e28728.

• Sekyrova P, Bohmann D, Jindra M, Uhlirova M (2010) Interaction between Drosophila bZIP proteins Atf3 and Jun prevents replacement of epithelial cells during metamorphosis. Development 137, 141-150. (Cover illustration)

• Konopova B, Jindra M (2008) Broad-Complex acts downstream of Met in juvenile hormone signaling to coordinate primitive holometabolan metamorphosis. Development 135, 559-568. (Cover illustration)

• Konopova B, Jindra M (2007) Juvenile hormone resistance gene Methoprene-tolerant controls entry into metamorphosis in the beetle Tribolium castaneum. Proc Natl Acad Sci USA 104, 10488-10493. (Highlighted article) (Faculty of 1000: Factor 9.0, Exceptional, New finding)

• Asahina M, Valenta T, Silhankova M, Korinek V, Jindra M (2006) Crosstalk between a nuclear receptor and β-catenin signaling decides cell fates in the C. elegans somatic gonad. Dev Cell 11, 203-211. (Faculty of 1000: Factor 3.0, Recommended, New finding)

• Jindra M, Gaziova I, Uhlirova M, Okabe M, Hiromi Y, Hirose S (2004) Coactivator MBF1 preserves the redox-dependent AP-1 activity during oxidative stress in Drosophila. EMBO J 23, 3538-3547.

• Gaziova I, Bonnette PC, Henrich VC, Jindra M (2004) Cell-autonomous roles of the ecdysoneless gene in Drosophila development and oogenesis. Development 131, 2715-2725.

• Uhlirova M, Foy BD, Beaty BJ, Olson KE, Riddiford LM, Jindra M (2003) Use of Sindbis virus-mediated RNAi to demonstrate a conserved role of Broad-Complex in insect metamorphosis. Proc Natl Acad Sci USA 100, 15607-15612.

• Uhlirova M, Asahina M, Riddiford LM, Jindra M (2002) Heat inducible transgenic expression in the silkmoth Bombyx mori. Dev Genes Evol 212, 145-151. (Cover illustration)

• Asahina M, Ishihara T, Jindra M, Kohara Y, Katsura I, Hirose S (2000) The conserved nuclear receptor Ftz-F1 is required for embryogenesis, molting and reproduction in Caenorhabditis elegans. Genes Cells 5, 711-723.

• Jindra M, Huang J-Y, Malone F, Asahina M, Riddiford LM (1997) Identification and mRNA developmental profiles of two Ultraspiracle isoforms in the epidermis and wings of Manduca sexta. Insect Mol Biol 6, 41-53.

• Jindra M, Malone F, Hiruma K, Riddiford LM (1996) Developmental profiles and ecdysteroid regulation of the mRNAs for two ecdysone receptor isoforms in the epidermis and wings of the tobacco hornworm, Manduca sexta. Dev Biol 180, 258-272.